We've all heard about Box Blight, which is ravaging across the land, ruining decorative clipped Box hedges left, right and centre, but it's worth mentioning…
It will prefer a warm climate though the roots like to be kept cool with a generous mulching. You might need to protect in the winter to keep the leaves from browning due to the cold. Should prune back hard in winter or early spring.
You can propagate by semi-ripe cuttings in the summer.